Specifically, the peak concentration at the injection site was 52.6% of the administered dose at one hour post-injection. As Abraham Al-Ahmad, an associate professor in pharmacology at Texas Tech University, pointed out in a blog post, the data showed that the injection site had the greatest accumulation of lipid nanoparticles, followed by the liver. The article’s interpretation of the biodistribution data is inaccurate. Changes in the level over time provide scientists with an idea of how long it takes for the body to eliminate the particles. The level of radioactivity acts as a proxy measurement for how much lipid nanoparticle is present in a given tissue. ![]() Researchers then then measured the level of radioactivity in tissues at different time points after injection. This data was obtained by injecting rats with a mix of lipid nanoparticles, which are identical to the ones used in the COVID-19 RNA vaccines, that carry a radioactive “label” (deuterium). We can assess the veracity of this claim by examining the biodistribution data in the technical documents submitted by Pfizer to Japan’s PMDA (see pages 5 and 6). Lipid nanoparticles enclose the RNA that encodes for the SARS-CoV-2 spike protein and enable cells to take up the RNA. The article’s claim about infertility stems from the misinterpretation that biodistribution data of lipid nanoparticles showed the ovaries to receive the highest amount among all organs and tissues. The data showed that the injection site retained the highest concentration of lipid nanoparticles over time, not the ovaries These come together in the article to ultimately paint a misleading picture of COVID-19 vaccine safety for readers. This review primarily focuses on the claims about the Pfizer biodistribution study, spike protein toxicity, and the RNA vaccine efficacy. This technique, in which a long list of inaccurate and/or misleading information is propagated repeatedly, is also known as firehosing. The article also contains a list of other claims, including several that were debunked previously (see our earlier reviews related to Geert Vanden Bossche, the Vaccine Adverse Events Reporting System, the Cleveland Study by Shrestha et al., comparison to the flu vaccine, and miscarriages in pregnant women). In the latest iteration of this claim, the TrialSite News article and others presented information from official documents submitted by Pfizer to Japan’s regulator Pharmaceuticals and Medical Devices Agency (PMDA) as evidence for its claim. Claims feeding this narrative have been propagated for years by anti-vaccine groups, taking on different forms over time-even though scientific evidence doesn’t support these claims, as shown in earlier reviews by Health Feedback on the flu vaccine and the human papillomavirus vaccine, and this fact-check on the tetanus vaccine by Africa Check. The narrative that vaccines affect fertility isn’t unique to COVID-19 vaccines. The article also received more than 1,800 interactions on Reddit, primarily in communities focused on conspiracy theories and COVID-19 skepticism. According to social media analytics tool CrowdTangle, the article received more than 14,000 interactions on Facebook to date, including more than 5,000 shares. Kirsch is the CEO of a digital money platform. REVIEW An article published by Steve Kirsch on TrialSite News in late May 2021 claimed that RNA vaccines would affect fertility. This turns the ovaries into a very large manufacturing plant to turn out toxic spike protein' the benefit of the vaccine is “minuscule“, with “less than a. ![]() ![]() FULL CLAIM: 'Biodistribution of lipid nanoparticles which carry the mRNA show that the ovaries get the highest concentration. The evidence so far doesn’t show that COVID-19 vaccination leads to a higher risk of adverse events during pregnancy or affects fertility. The level of spike protein generated through COVID-19 vaccination is much lower than the levels associated with damage during infection. There is evidence indicating that spike protein during infection can lead to damage, but this isn’t representative of the situation in vaccination. Real-world evidence shows that the COVID-19 RNA vaccines are highly effective at preventing illness and death.
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